Hormone Replacement Therapy Research Today is a free monthly online journal that collates and summarizes the latest research about Hormone Replacement Therapy, including details on hrt, menopause, natural hrt, effects, risks.

Testosterone replacement increases vasodilatory reserve in androgen-deficient female rats.

Cooper BC, Gokina NI, Osol G

Department of Obstetrics and Gynecology, University of Vermont College of Medicine, Burlington, Vermont, USA. brian-cooper3825@hotmail.com <brian-cooper3825@hotmail.com>

Testosterone replacement leads to increased coronary pressure-induced tone and vasodilatory reserve in oophorectomized rats. The mechanisms involve changes in endothelial nitric-oxide modulation of smooth-muscle constriction and are not a result of the peripheral conversion of T to estrogen.

Published 5 February 2007 in Fertil Steril, 87(2): 422-5.
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